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Background and Purpose: according to the studies that have been conducted so far, the corona virus has more severe clinical consequences in diabetic patients than in non-diabetic cases;Therefore, the present study was conducted with the aim of investigating the severity of the disease and mortality in patients infected with the Coronavirus between these 2 groups. Materials and Methods: In this cross-sectional-analytical study, the clinical records of 185 hospitalized patients with a positive laboratory diagnosis of Covid-19 were reviewed from February 14 to February 26, 2020. The patients were divided into 2 non-diabetic (95 people) and diabetic (90 people) groups, and their clinical symptoms and blood biochemical parameters were compared. Results: Based on the results, most of the patients were male and compared to non-diabetic patients, the diabetic group was significantly older (P=0.01). In this study, the disturbance in paraclinical factors such as d-dimer, BUN, VBG and lymphopenia in diabetic patients was significantly higher than in the control group, which indicates the need for more care in diabetic patients. Conclusion: it is suggested to follow health protocols for people with land diseases, be more careful., therefore, more extensive research with larger sample sizes is needed to achieve more accurate results. [ FROM AUTHOR] Copyright of Journal of Pharmaceutical Negative Results is the property of ResearchTrentz and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
Background: With an increase in the spread of the pandemic, ailments related to the COVID illness started to appear. Patients with COVID - 19 infection experienced a worse outcome with an increase in the prevalence of opportunistic infections in the infected person especially Mucormycosis. It was recognized that people with diabetes, cancer, patients undergoing chemotherapy and other immune-compromised conditions can develop Mucormycosis. Systemic steroids and other immune-modulating agents which are the mainstay of treatment for COVID-19 predisposes to the chance of developing invasive fungal infections. Methodology: Here we provide a retrospective analysis in which out of 212 patients who were subjected to screening 13 individuals were KOH mount positive with unique clinical characteristics as well as demographic and therapeutic profile. The information was gathered retrospectively at a single facility that serves a sizable group of patients with varying severity of the Corona virus infection. Results: Of the total in-patients taken into consideration 13 were diagnosed with mucormycosis post COVID-19 infection. The median age was greater among individuals who survived the infections (49.5 years) and those with severe COVID had high chance of dying (23.8), with an overall mortality rate of 64.3 percent. Additionally 61.5 percent of patients had diabetes mellitus and 75% of them died. 11 patients (84.6%) had previously been on steroids for COVID-19. Both the individuals who survived and succumbed to the disease had same level of hyperglycemia. Conclusion: The prevalence of mucormycosis among COVID-19 patients appears to be rising, which may be attributed to increasing usage of steroid, a potential immunocompromised state brought about by the virus per se and the co-morbid conditions. A high index of suspicion and early diagnosis is necessary to bring down the mortality rate This is in addition to the preventive measures and sensible use of immunemodulators. [ FROM AUTHOR] Copyright of Journal of Pharmaceutical Negative Results is the property of ResearchTrentz and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
Background: The prevalence of people with diabetes mellitus increases with the high number of Covid-19. Poor diet, low physical activity, and severe stress levels can increase blood glucose levels in people with diabetes mellitus. During the Covid-19 pandemic, changes in diet, physical activity, and stress levels were foundObjective: To examine diet, physical activity, and stress levels of people with diabetes mellitus during the Covid-19 pandemic. Methods: This study uses a literature review study method. The data source used comes from the Google Scholar and Science Direct database from the 2018-2022 time range with the keywords diet, physical activity, and stress levels of people with diabetes mellitus during the Covid-19 pandemic. The results of all articles that have gone through the screening process open 21 articles. Results:. 6 of the 21 articles stated that there were changes in diet, physical activity, and stress levels of people with diabetes mellitus before and during the Covid-19 pandemic. 5 of 21 articles stated that there was a relationship between diet and blood glucose levels in people with diabetes mellitus. 4 of 21 articles stated that there was a relationship between physical activity and blood glucose levels, while 1 of 21 stated that there was no relationship between activity and blood glucose levels in people with diabetes mellitus. 5 of 21 articles stated that there was a relationship between stress levels and blood glucose levels in people with diabetes mellitus. Conclusion: There are changes in diet, physical activity, and stress levels of people with diabetes mellitus before and during the Covid-19 pandemic. There is a relationship between diet, physical activity, and stress levels with blood glucose levels in people with diabetes mellitus. People with diabetes mellitus are advised to adjust their diet, do regular physical activity, and perform stress management. (English) [ FROM AUTHOR] Latar Belakang: Prevalensi penderita diabetes melitus meningkat seiring tingginya angka Covid-19. Pola makan buruk, aktivitas fisik rendah dan tingkat stres berat dapat meningkatkan kadar glukosa darah penderita diabetes melitus. Pada masa pandemi Covid-19 ditemukan perubahan pola makan, aktivitas fisik, dan tingkat stress. Tujuan: Mengkaji pola makan, aktivitas fisik, dan tingkat stres penderita diabetes melitus di masa pandemi Covid-19. Metode : Penelitian ini menggunakan metode studi literature review. Sumber data yang digunakan berasal dari database Google Scholar dan Science Direct dari rentang waktu 2018-2022 dengan kata kunci pola makan, aktivitas fisik, dan tingkat stres penderita diabetes melitus di masa pandemi Covid-19. Hasil keseluruhan artikel yang telah melalui proses screening berjumlah 21 artikel. Hasil:. 6 dari 21 artikel menyatakan ada perubahan pola makan, aktivitas fisik, dan tingkat stres penderita diabetes melitus sebelum dan selama pandemi Covid-19. 5 dari 21 artikel menyatakan ada hubungan pola makan dengan kadar glukosa darah penderita diabetes melitus. 4 dari 21 artikel menyatakan ada hubungan aktivitas fisik dengan kadar glukosa darah sedangkan 1 dari 21 menyatakan tidak ada hubungan aktivitas dengan kadar glukosa darah penderita diabetes melitus. 5 dari 21 artikel menyatakan ada hubungan tingkat stres dengan kadar glukosa darah penderita diabetes melitus. Kesimpulan: Ada perubahan pola makan, aktivitas fisik dan tingkat stres penderita diabetes melitus sebelum dan selama pandemi Covid-19. Ada hubungan pola makan, aktivitas fisik, dan tingkat stres dengan kadar glukosa darah penderita diabetes melitus. Penderita diabetes melitus disarankan untuk mengatur pola makan, melakukan aktivitas fisik secara teratur, dan melakukan manajemen stres. (Indonesian) [ FROM AUTHOR] Copyright of Jurnal Sosial dan Sains (SOSAINS) is the property of Green Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
BACKGROUND. Coronavirus disease 2019 (COVID-19) is one of the main global health problems of the twenty-first century, with more than one-hundred million people infected and more than two million deaths. The immunosuppression caused by SARS-CoV-2 infection along with steroidal treatment, hyperglycaemia and elevated ferritin levels creates the perfect environment for opportunistic infections such as mucormycosis. COVID-19-associated mucormycosis carries a high mortality rate. Therefore, in addition to antifungal therapy and aggressive surgical debridement of necrotic tissue, strategies to improve glycaemic index is the key factor in order to obtain a favourable outcome. MATERIAL AND METHODS. For the purpose of this article, the PubMed databases were searched using MeSH descriptors and the Boolean operator "AND" for the terms "rhinosinusal" and "mucormycosis" and "diabetes", between February 2019 – December 2021. Clinical characteristics, therapy and outcome data were gathered and compared to what has previously been reported in the literature. Also, we report the case of a 68-year-old patient with uncontrolled type 2 diabetes mellitus, who developed mucormycosis during post-COVID period, to underline the need of early detection of this potentially deadly fungal illness. RESULTS. The clinical and imaging evaluation revealed no evidence of disease recurrence, at one- and two-months' follow-ups. CONCLUSION. In this context, we would like to emphasize the importance of a high index of suspicion for mucormycosis in patients with COVID-19 infection, with pre-existing medical disorders, presenting with rhino-orbital or rhino-cerebral symptomatology. [ FROM AUTHOR] Copyright of Romanian Journal of Rhinology is the property of Romanian Rhinologic Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
It is well established that people with diabetes are more likely to have serious complications from COVID-19. Nearly 1 in 5 COVID-19 deaths in the African region are linked to diabetes. World Health Organization (WHO) finds that 18.3% of COVID-19 deaths in Africa are among people with diabetes. In this paper, we have formulated and analysed a mathematical comorbidity model of diabetes-COVID-19 of the deterministic type. The basic properties of the model were explored. The basic reproductive number, equilibrium points, and stability of the equilibrium points were examined. Sensitivity analysis of the model was carried on to determine the impact of the model parameters on the basic reproductive number R 0 of the model. The model had a unique endemic equilibrium point, which was stable for R 0 > 1. Time-dependent optimal controls were incorporated into the model with the sole aim of determining the best strategy for curtailing the spread of the disease. COVID-19 cases from March to September 2020 in Ghana were used to validate the model. Results of the numerical simulation suggest a greater number of individuals deceased when the infected individual had an underlying condition of diabetes. More so, the disease is endemic in Ghana with the basic reproduction number found to be R 0 = 1.4722. The numerical simulation of the optimal control model reveals the lockdown control minimized the rate of decay of the susceptible individuals whereas the vaccination led to a number of susceptible individuals becoming immune to COVID-19 infections. In all, the two preventive control measures were both effective in curbing the spread of the disease as the number of COVID-19 infections was greatly reduced. We conclude that more attention should be paid to COVID-19 patients with an underlying condition of diabetes as the probability of death in this population was significantly higher. [ FROM AUTHOR] Copyright of International Journal of Mathematics & Mathematical Sciences is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
Aims: To investigate the clinical outcome of patients with confirmed COVID-19 who had diabetes mellitus as a comorbidity at King Abdulaziz University Hospital, Jeddah. Methods: Retrospective study conducted at an academic tertiary hospital, included 147 adults with a confirmed diagnosis of diabetes mellitus, and a confirmed diagnosis of COVID-19. The data included: age, gender, body mass index (BMI), HbA1c level, medications, co-morbidities, length of hospital stay, the clinical outcome of the patients, and complications related to COVID-19 during the hospital stay. Data were analyzed using Stata version 16. Results: 54% had HbA1c levels >9%. With regard to other health problems, 73% reported having health problems. 31% and 18% required ICU admission and intubation respectively. Median length of hospital stay was 12 days. Regarding clinical outcomes, the majority recovered without complications (78%), while 9% recovered with complications and 13% died. Conclusions: The difference in outcomes based on HbA1c levels was not statistically significant, therefore there was no difference in other clinical parameters based on the different levels of HbA1c. Further, large studies should be conducted to determine the relationships between diabetes, antidiabetic medications, and COVID-related morbidity and mortality. [ FROM AUTHOR] Copyright of Egyptian Journal of Hospital Medicine is the property of Egyptian Journal of Hospital Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
ABSTRACT
During the unprecedented times of the COVID 19 pandemic, the lives of people with diabetes have been severely impacted. This article discusses the extent of this impact presenting the obstacles and challenges from the perspective of the patient, including specifics of practical day-to-day diabetes self-management routines. Since the COVID19 outbreak, certain psychosocial factors have been amplifieddue tothe manner in whichmainstream media and policy makers have carelessly emphasized the vulnerability of people with diabetes. The authors discuss the increased importance of support networksdue to people living in isolation and quarantine. Anewlayer of complexity has been added to the already difficult task of managing one's diabetes and ithasincreasedanxiety and stress levels. Guidelines and tips for people living with diabetes are discussed based on theauthors' personalexperiences as well as those ofthe diabetes associations they work with.